The First Sham-Controlled PCI Trial In Stable Patients

ORBITA enrolled 200 patients with severe (≥70%) single-vessel coronary stenoses as assessed by angiography. Prior to randomization, all of them received six weeks of medication optimization and assessments with cardiopulmonary exercise testing, symptom questionnaires, and dobutamine stress echocardiography.

Six-weeks after their treatments, all the patients underwent the assessments they had before randomization. The primary endpoint was difference in...