Start-Up Spotlight: Kephalios, Simplifying Targeted Mitral Valve Repair

 
• By Tina Tan

Investors are betting on mitral valves as the next "big thing" in cardiology as interest in technologies to treat mitral regurgitation heat up among the big heart players. Competition among the developers of transcatheter mitral valve repair systems is intensifying as they jostle for attention, but start-up Kephalios believes the simplicity of its technology, which precisely targets repair of the defective valve, will help it stand out.

Start-up Spotlight

Of the estimated 4 million patients in the US and Europe suffering from severe mitral valve regurgitation, less than 4% undergo a mitral intervention to fix it annually, according to Kephalios, a French start-up seeking a slice of this pie with its Kalios balloon-adjustable TMVR system.

Mitral valve leaflets that do not close completely may allow blood to regurgitate back into the left atrium rather than...

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