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New Anti-Epileptic Drug Formulations Try To Overcome Tolerability Problems

 
• By Bridget Silverman

Much of the drug development activity in epilepsy is focused on improving the existing treatments.

Compared with many therapeutic areas, epilepsy has an unusually strong pipeline of new drugs that are not novel molecular entities – novel formulations using the 505(b)(2) NDA pathway, which allows sponsors to incorporate by reference parts of the innovator drug’s NDA.

“In the epilepsy market, new chemical entities, or NCEs, generally lack the same appeal that would typically be associated with a new drug for other indications,” Supernus Pharmaceuticals Inc....

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