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Synthetic Biologics Thinks Statins May Get At Root Of IBS-Constipation

 
• By Emily Hayes

Biotech set to develop patented special-release statin formulation for a new approach to constipation-predominant irritable bowel syndrome – methane gas. The same research also underpins development of Salix’ Xifaxan for diarrhea-predominant IBS.

Synthetic Biologics Inc.is developing an oral, statin-based candidate for chronic use that it thinks can get at the root cause of constipation-predominant irritable bowel syndrome – the overgrowth of a particular type of intestinal bacteria called methanogens.

During an investor briefing on Sept. 16, the company said that it has developed a plan that should enable it to have Phase II data by Autumn 2015 for SYN-010,...

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