Tredaptive Safety Hazards Cast Shadow Over AbbVie’s Niaspan

HPS2-THRIVE investigators say serious adverse bleeding and infection events are most likely due to the niacin component of Merck’s Tredaptive and advise caution using niacin in light of the risks. Abbvie’s Niaspan is the most likely branded casualty of the news, but the drug will be off-patent soon.