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Doctors Urge Caution In Interpreting FDA’s SGLT2 Warning

 
• By Emily Hayes

Endocrinologists raise concerns over FDA case reports because diabetic ketoacidosis may be a risk for type 1 diabetes patients taking SGLT2 inhibitors, but it is very rare in type 2 diabetes.

Some endocrinologists are prescribing a cautious attitude toward FDA’s recent warning on the link between SGLT2 inhibitors and diabetic ketoacidosis in type 2 diabetes until more details are available about the cases reported.

FDA issued a safety announcement on May 15 noting that 20 cases of diabetic acidosis, including diabetic ketoacidosis (DKA), ketoacidosis or ketosis, were reported in patients who had taken SGLT2...

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