Genomics-Driven Trials Built To Be Fast And Flexible

Pioneering enrollment strategies are coupled with adaptive statistical designs in the next wave of basket trials from NCI, ASCO and Novartis.

Drug candidates aren't the only innovations being tested in a wave of trials using new "basket" designs. Three large-scale basket trials are gearing up that will be crucial tests of a paradigm-shifting approach to clinical trial conduct and enrollment.

The trials – the National Cancer Institute-MATCH study, Novartis AG's SIGNATURE program, and the American Society for Clinical Oncology's TAPUR trial – will take advantage of a revolution in...

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