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Inflammation A Clue Left In ACCELERATE CETP Wreckage

 
• By Emily Hayes

Blood pressure and C-reactive protein were modestly increased in the ACCELERATE trial of Lilly’s CETP inhibitor evacetrapib, but what exactly torpedoed the trial is still a mystery.

Results from the ACCELERATE outcomes study of Eli Lilly & Co.’s CETP inhibitor evacetrapib suggest that inflammation may have played a role in the trial’s failure, but investigators say it’s really still too early to say what happened.

Full results from ACCELERATE were presented at the American College of Cardiology annual meeting on April 3

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