NICE Backs Xgeva for Oncology But Excludes Prostate Cancer Indication

 
• By Faraz Kermani

A significant discount from Amgen has left NICE more than happy to pass Xgeva, but it still found economic grounds to reject the company’s application for a prostate cancer indication.

In a rare occurrence for any drug navigating its way through the UK’s reimbursement system, Amgen Inc.’s Xgeva (denosumab) for the treatment of skeletal events in some cancer patients has fairly flown through the National Institute for Health and Clinical Excellence’s evaluation process. Although the company did not get everything it wanted from the health-cost regulator, the discount Amgen offered the NHS means that it can now rest assured that the uptake of Xgeva is only a brief matter of time.

NICE gave the thumbs up to Xgeva as an option for preventing skeletal-related events, including pathological fracture, radiation to bone,...

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