EMA Pushes For Industry Collaboration On Psychiatric And Psychedelic Drug Innovations

 

The European Medicines Agency wants to work with other regulators as well as industry, scientists and patients to “find solutions for the most pertinent problems in psychedelic research” and improve treatment options for psychiatric disorders more broadly, says the agency.

EU Helps Sponsors To Steer National Fee Requirements Under Clinical Trials Regulation

 
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A working group of EU regulators has developed a comprehensive repository of fee requirements relating to the Clinical Trials Regulation to help sponsors navigate the diverse demands of member states in the European Economic Area.

Romanian Raids On Boehringer Result In Eight-Figure Fine For COPD Market Abuse

 
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Boehringer Ingelheim “made it more difficult” for doctors to prescribe generic versions of its Spiriva (tiotropium) inhalers, Romania’s Competition Council has found, as it levied a fine of more than $25m on the German originator.

EMA’s Conflict Of Interest Rules Must Not Limit Access To Experts And Risk Innovation, Warns Industry

 

The European Medicines Agency has published new policies on handling conflicts of interests for its scientific committee members, experts and management board members.


UK’s MHRA To Offer Private Meetings For Innovative RWE Strategies

 

The MHRA’s new scientific dialog program will offer drug developers “closed-door meetings” that will offer “confidential, commercially sensitive discussion” with its staff to help them “refine” their real-world evidence generation strategies.

EU Pharma Reform & Reducing Reliance On Asian Imports: What To Expect in 2025

 

The European Commission's 100-day countdown to deliver a Critical Medicines Act, aimed at improving the EU's resilience to supply chain disruptions and price volatility, began last December. Meanwhile, negotiations over the proposed package that will reform the over 20-year-old EU pharmaceutical legislation are now in the hands of the Council of the EU. The Pink Sheet examines what to expect for these key pieces of legislation this year.

MHRA: New UK Point Of Care Legislation Will Remove ‘Regulatory Barriers’ To Innovation

 

The UK’s “world-first” tailored regulatory framework for point of care manufacturing is set to enter into force this summer.

How Novo’s Acquisition Of Catalent Cleared European Regulators

 

Now that one of the most controversial pharma M&As of 2024 has closed, the Pink Sheet looks at whether overtures to concerned customers and extended prenotification discussions helped Novo and Catalent seal the deal.


Game-Changing EU-Level HTA Regs Must Allow For Lessons To Be Learned

 

EU joint clinicals assessments introduced under the HTA Regulation have now gone live for cancer medicines and advanced therapies.

EU Consultation Deadline Looms For Pharmacovigilance Rules Update

 

Stakeholders have until 15 January to respond to a European Commission proposal that aims to harmonize pharmacovigilance activities by marketing authorization holders, national competent authorities and the European Medicines Agency.

Why 2025 Could See A Surge In EMA Approval Opinions For ATMPs

 

Marketing authorization applications for five new advanced therapy medicinal products were filed with the European Medicines Agency in 2024, the highest number in any year since 2020. The Pink Sheet looks at these and two other ATMPs that might get the thumbs up from the European Medicines Agency in 2025.

Spanish Health Ministry Targets Efficiency With New Medicine Pricing Rules

 

A draft royal decree would pave the way for more transparency in pricing and reimbursement decision-making processes and boost competition to increase the participation of generic medicines.


EU CHMP Opinions And MAA Updates

 

This is an update of recommendations from the European Medicines Agency's Committee for Medicinal Products for Human Use on the authorization of new medicines in the EU, and updates on EU marketing authorization changes recommended by the CHMP.

Ozempic & NAION: EU Safety Panel Continues Probe Into Link With Eye Condition

 

The European Medicines Agency says it will take appropriate measures to update the Ozempic’s package leaflet if new evidence arises.

New EU Filings

 

Doxecitine/doxribtimine, UCB’s investigational orphan drug for pediatric and adult patients with thymidine kinase 2 deficiency, is among the latest products that have been filed for review by the European Medicines Agency for potential EU marketing approval.

New EU Approvals

 

The Pink Sheet's list of EU centralized approvals of new active substances has been updated to include Alhemo, Novo Nordisk's product for the prevention of bleeding in patients with hemophilia A and FVIII inhibitors or hemophilia B and FIX inhibitors.


EU To Pilot Single Assessment Of Multinational Drug/IVD Combination Studies

 
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EU regulators have approved a strategy to streamline the submission and approval of studies that involve the simultaneous investigation of a medicinal product, an IVD, and/or a medical device. The strategy involves rolling out seven cross-sector projects over the next few years.

AI-Generated Plain Language Summaries Of Trial Results Can Save Time, But Need A Human Touch

 
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Staburo’s Kathi Künnemann examined the utility of artificial intelligence in developing plain language summaries for clinical trials results.

UK’s Rare Therapies Launch Pad To Be ‘Fully Operational’ By Year-End

 

“Significant progress” has been made in setting up the UK’s Rare Therapies Launch Pad pilot scheme, which will construct a “new regulatory pathway tailored specifically for ultra-rare diseases,” a senior scientist involved in the project says.

Move Towards ‘Default Disclosure’ In Revamped EU Transparency Guidance Concerns Industry

 

New guidance on data transparency from European medicines regulators will mean more administrative burden for small and medium sized companies.