US Tariffs: With 50% Of US Generics From India, Industry Ponders If MAHA Will Trump MAGA

 
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US President Trump’s plan for a “25% or higher” tariff on pharmaceuticals promises to have a far-reaching impact, from higher prices and drug shortages to increased onshoring of manufacturing in the US. Is MAGA worth the chaos it might create for MAHA? The Indian industry shares its views.

Japan Set To Approve Broad Revisions To PMD Act

 
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Multiple, wide-ranging revisions to Japan's PMD Act, including provisions on pediatric R&D, use of real-world data and cell therapies, look set to receive formal political approval within the next few months. There is also more clarity on a controversial scheme to support venture companies.

PhRMA Still All In For Trump Despite Chaos Hitting US Health Sector

 

The pharmaceutical industry has been quiet on Trump's early federal government overhauls that could harm the drug business, still betting he will help produce better results than Biden.

CMS Layoffs Broader Than Reports Indicate, Former Administrator Brooks-LaSure Says

 
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The "interwoven" nature of the offices within the agency likely means Medicare and Medicaid benefits may be disrupted by staff cuts despite assurances from the administration, Brooks-LaSure warned.


Pharma Industry Wants Easier Access To England’s Revamped NHS Data Sharing System

 

The pharmaceutical industry was not sufficiently involved in designing updates to England’s health data infrastructure, leading to a “misalignment” between company needs and what is currently being delivered, according to the results of a survey by the Association of the British Pharmaceutical Industry.

France Gives Fresh Impetus To Economic Evaluations In Five Year Strategic Plan

 

France’s health technology appraisal body, HAS, is putting more emphasis on the importance of economic evaluations in light of the rising costs of health technologies, including medicines and medical devices, and increasing budgetary pressures.

EU HTA Regulation: Joint Scientific Consultations Are An ‘Important Strategic Opportunity’

 

Manufacturers should make use of joint scientific consultations under the EU Health Technology Assessment Regulation, but they must pay close attention to the selection criteria as consultation slots are limited, experts say.

Congress Can, But Likely Will Not, End Part D Stabilization Demo

 
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Congress may be empowered to change the Part D stabilization demo, but a health policy expert said CMS is more likely to repeal, adjust or replace the program.


Brazil Consults On How To Price Advanced Therapies

 

Brazil’s drug regulator ANVISA has also published its first post-marketing authorization monitoring reports on advanced therapies Yescarta, Zolgenma, Kymriah, Carvykti and Luxturna.

Ogsiveo And Winrevair Among Latest Orphan Drugs To Secure Early Access Funding In France

 

HAS, the French health technology assessment body, has issued positive recommendations for several orphan drugs, including for Vyloy, which was provisionally rejected for reimbursement in the UK last year.

PICO Exercises: A Glimpse Into Future Joint Clinical Assessments Under EU HTA Regulation

 

The European Commission has released three exercises to help pharma companies prepare for joint clinical assessments under the new EU Health Technology Assessment Regulation. Experts explain how manufacturers should interpret these and what their limitations are.

Navigating the Unknown: EU HTA Regulation’s Impact On Commercial Confidentiality

 

Company dossiers submitted for EU-level joint clinical assessments under the Health Technology Assessment Regulation will be made public. This could conflict with other strategic business decisions and should be planned for in advance, experts say.


Tipping Point: Tariffs Create Uncertainty, Risk Long-Term Price Increases, Shortages

 
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President Trump’s 10% tariff on active pharmaceutical ingredients and finished dosage forms could push some generic drug makers to exit therapeutic categories if they cannot absorb the new costs, which could lead to shortages.

US Medicare Agency Brings Back Familiar Faces For Trump 2.0

 

Several first-term Trump veterans are returning to leadership roles at the US Centers for Medicare and Medicaid Services ahead of the expected confirmation of Mehmet Oz to lead the agency.

Medicare Part D Redesign: More Firms See New Discounts Offsetting Spending Cap Benefit

 
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AbbVie, J&J, Merck and Pfizer discussed recent projections for the redesign's impact.

Gene Editing Therapy Casgevy Now Funded In 8 Countries But French Access Withdrawn

 

The world’s first CRISPR gene editing therapy, Casgevy, has been made available to patients with sickle cell disease in England, adding to access arrangements in the US, Austria, Bahrain, Germany, Luxembourg, Italy and Saudi Arabia.


Uncertainty For Pharma At All-Time High As Controversial Finance Bill Returns To French Parliament

 

Debate on how to manage drug spending continues in France despite an ongoing disagreement between industry and the government about whether there was €1.2bn overspend on medicines in 2024.

UK’s MHRA Revamps Innovative Pathway And Tightens Entry Criteria

 

Companies that are admitted to the UK’s revised innovative licensing and access scheme will be mandated to work with the regulator on developing a target development profile for their product.

Medicare 2027 Negotiating Class: Austedo, Linzess, Xifaxan May Face Generic, OTC Price Comparators

 
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Manufacturers will address what constitutes appropriate therapeutic alternatives for the selected drugs as part of the negotiation process.

Medicare Price Negotiation Will Continue Under Trump With Possible ‘Improvements’

 
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HHS Secretary nominee Robert F. Kennedy Jr. discussed the Trump Administration's support for Medicare price negotiation during his confirmation hearing.