Manufacturing

Aurobindo Says US Tariffs ‘Not A Challenge’ For Now

 
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President Trump imposed reciprocal tariffs on countries with duties on US exports 13 February. When asked on 7 February about the impact of US tariffs, Aurobindo said it has alternatives in place to deal with them.

Compounded GLP-1s For Obesity: Is The Genie Out Of The Bottle?

 
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Patient demand for compounded versions of FDA approved obesity drugs is unlikely to dissipate, even if semaglutide’s “shortage” status is resolved. The issue likely will continue to be a high profile concern for the brand industry.

Africa Partners With PIC/S To Elevate GMP Standards And Accelerate AMA’s Rollout

 

Efforts have stepped up to enhance Africa’s capacity to meet international good manufacturing practice standards, empower regulators across the continent, and drive sustainable growth in the pharmaceutical sector.

EU Launches Biotech Hub With ‘Critical Information’ About Regulations & Funding

 

The European Commission’s new biotech and biomanufacturing hub will make it easier for innovative biotech companies to find legislative documents, funding information and guidance to help them bring new products to the market.


Feedback Sought To Shape Highly Awaited EU Law On Cutting Dependency On Asian Imports

 

Momentum is building around the European Commission’s race to propose a Critical Medicines Act, which aims to tackle drug shortages and create a better framework for establishing manufacturing facilities of essential medicines in the EU.

UK MHRA Consults On The Way For Personalized mRNA Cancer Therapies

 

The UK’s drug regulator is developing a “clear and streamlined” regulatory pathway for individualized cancer mRNA immunotherapies.

Pharma Industry Calls For Policy Changes At EU Level To Address Shortages

 

European regulators should develop a harmonized medicines shortages prevention and mitigation system and look to target the root causes of shortages, says pharmaceutical industry federation EFPIA.

EU Offers Funding To Safeguard Innovation Under New Health Data Sharing Rules

 

Europe’s public-private Innovative Health Initiative is seeking contenders for two research projects relevant to pharmaceuticals, one relates to the incoming European Health Data Space Regulation and the other focuses on reducing exposure to medicines containing per- and polyfluoroalkyl substances.


Exit Interview: US FDA’s Patrizia Cavazzoni Says CDER Staff In ‘Best Place Possible’

 
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During a virtual appearance at a CERSI meeting two days after announcing retirement plans, the CDER director also said she wished agency reviews of unapproved drugs could be published.

MHRA: New UK Point Of Care Legislation Will Remove ‘Regulatory Barriers’ To Innovation

 

The UK’s “world-first” tailored regulatory framework for point of care manufacturing is set to enter into force this summer.

How Novo’s Acquisition Of Catalent Cleared European Regulators

 

Now that one of the most controversial pharma M&As of 2024 has closed, the Pink Sheet looks at whether overtures to concerned customers and extended prenotification discussions helped Novo and Catalent seal the deal.

Key India Regulatory Advances To Watch In 2025

 

2024 saw important regulatory changes in India including in areas such as GMP, clinical trials and efforts to rein in unethical marketing practices. Further action is expected to play out in the new year as well.


US FDA Blocks 11 Viatris Products, Except Four With Shortage Concerns

 
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Viatris’ oral finished dose manufacturing facility in Indore, India, was slapped with a US Food and Drug Administration import alert and warning letter.

US FDA’s Inspections Reorg: Changes In Form 483 Responses, Faster Engagement With Product Centers

 
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The agency’s compliance directors also discussed expectations for greater inspection and review efficiencies as part of the 1 October reorganization during a recent FDLI conference.

PIC/S Sets Global Standards For Remote GMP Inspections

 
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Final guidance on remote and hybrid good manufacturing practice inspections from the global inspectorate body, the PIC/S, aims to enhance inter-agency communication, improve reliance on inspections and ensure efficient use of global resources.

Rx Enforcement In 2025: Shift Away From Opioid Makers But Tougher Approach On Ad/Promo

 
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The compounding industry ties for Martin Makary, President-elect Trump’s candidate to lead the FDA, could mean less compounding enforcement, experts said, but government officials said their enforcement focus will remain nonpartisan.


US FDA Takes Lilly’s Mounjaro, Zepbound Off Shortage List But Gives Compounding Grace Period

 
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Compounding pharmacies have 60 days, and outsourcing facilities 90 days, to transition patients to branded products.

Inertia For Supply Chain Change May Stick Even If BIOSECURE Fails

 

Efforts to de-risk the pharma supply chain’s reliance on China likely will not completely disappear if the BIOSECURE proposal dies.

UK MHRA Reminds Industry Of Looming Deadline For New Packaging Requirements

 

More than 90% of companies have submitted new medicines packaging artwork to the UK’s drug regulator, the MHRA. The agency urges the remaining marketing authorization holders of its 31 December deadline to comply with the new Windsor Framework arrangements.

India Regulatory Reform: ‘Redeliberation’ At SECs Tightened, ‘Unnecessary Load’ Reduced

 

India continues to reform biopharma regulatory processes and widen digitization efforts. The regulator will curb "re-deliberations" at subject expert committee meetings unless applicants furnish new data.