Distribution/Supply Chain

Beyond Tariffs: The Silver Lining Of The US Pharma Security Investigation

 

An investigation by the US Secretary of Commerce into pharmaceutical imports gives industry an opportunity to comment. AAM CEO John Murphy talked to Pink Sheet's sister publication Scrip about the latest developments.

Pharma Still Nervous While Riding Trump’s Tariff Rollercoaster

 

The rollout of Trump’s plan has been a policy whiplash, but despite a 90-day pause on tariffs, the US president still appears to be holding a grudge with industry over drug pricing.

US Pharma Tariff Reprieve May Be Ending

 

Sector-specific tariffs, including on pharmaceuticals, could be announced as early as this week.

Japan Pushes Generic Industry Reforms Via New Govt Fund

 
• By 

Amid ongoing generic drug supply problems, Japan's government is to set up a new fund to support corporate investments geared towards manufacturing and consolidation.


EU’s Critical Medicines Act: A Major Milestone Or Too Weak?

 

Newly proposed legislation for bolstering the EU’s drug manufacturing capacity and reducing its overreliance on foreign manufacturers includes a number of measures, such as a requirement for EU countries to prioritize the security of supply over price when procuring drugs.

EU Critical Medicines Act Unveiling On 11 March–Industry Backs, But Urges Caution

 

The new act aims to tackle drug shortages and create a better framework for establishing manufacturing facilities of essential medicines in the EU. It should recognize differences between generics and innovative products, says industry group EUCOPE.

Lilly’s Lower-Cost Zepbound Options Could Ease Patient Transition From Compounded GLP-1s

 
• By 

Lilly is broadening the range of single-use vial dosage forms of its obesity drug and lowering prices of existing doses for self-paying customers, but maintains it can handle increased demand as compounding ends.

Lilly $27Bn US Manufacturing Investment Linked To Trump’s Tariff, Tax Agenda

 

Eli Lilly's move is said to be part of broader industry campaign to invest in America and avoid President Trump's tariffs, but the company also said tax reform is necessary to make the investments.


US FDA Employs Familiar Strategy In Ending Novo’s Wegovy, Ozempic Shortage

 
• By 

A declaratory order removing semaglutide from the FDA shortages list duplicates much of the language in a December decision still in litigation that declared Eli Lilly’s tirzepatide products Mounjaro and Zepbound were no longer in shortage.

Tipping Point: Tariffs Create Uncertainty, Risk Long-Term Price Increases, Shortages

 
• By 

President Trump’s 10% tariff on active pharmaceutical ingredients and finished dosage forms could push some generic drug makers to exit therapeutic categories if they cannot absorb the new costs, which could lead to shortages.

Trump And Tariffs Top Generic Industry Concerns

 
• By 

At a lively AAM Access! conference in Florida, AAM President and CEO John Murphy acknowledged the negative effects of potential tariffs, but also suggested that the second Trump Administration could be an opportunity for the generics and biosimilars sectors to advance market reforms.

Feedback Sought To Shape Highly Awaited EU Law On Cutting Dependency On Asian Imports

 

Momentum is building around the European Commission’s race to propose a Critical Medicines Act, which aims to tackle drug shortages and create a better framework for establishing manufacturing facilities of essential medicines in the EU.


Pharma Industry Calls For Policy Changes At EU Level To Address Shortages

 

European regulators should develop a harmonized medicines shortages prevention and mitigation system and look to target the root causes of shortages, says pharmaceutical industry federation EFPIA.

MHRA: New UK Point Of Care Legislation Will Remove ‘Regulatory Barriers’ To Innovation

 

The UK’s “world-first” tailored regulatory framework for point of care manufacturing is set to enter into force this summer.

Health Canada Proposes Major Regulatory Overhaul To Combat Drug, Device Shortages

 
• By 

Canada’s health products regulator is inviting feedback on a range of new and revised guidelines and regulatory tools that explain how drug and device companies will be able to comply with significant changes proposed to its shortages framework.

US FDA Takes Lilly’s Mounjaro, Zepbound Off Shortage List But Gives Compounding Grace Period

 
• By 

Compounding pharmacies have 60 days, and outsourcing facilities 90 days, to transition patients to branded products.


Inertia For Supply Chain Change May Stick Even If BIOSECURE Fails

 

Efforts to de-risk the pharma supply chain’s reliance on China likely will not completely disappear if the BIOSECURE proposal dies.

EMA Encourages Swift Data Insertion As European Shortages Monitoring Platform Goes Live

 

Marketing authorization holders are being encouraged to insert their data on shortages of centrally authorized medicines in the new platform before it becomes mandatory to do so in February 2025.

Nordic Countries Launch ‘English-Only’ Packaging Pilot To Tackle Medicine Shortages

 

Drug companies are being invited to participate in a new pilot project that the five Nordic countries will run to see if they can improve the availability of certain critical products that are used in hospitals.

UK MHRA Reminds Industry Of Looming Deadline For New Packaging Requirements

 

More than 90% of companies have submitted new medicines packaging artwork to the UK’s drug regulator, the MHRA. The agency urges the remaining marketing authorization holders of its 31 December deadline to comply with the new Windsor Framework arrangements.