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Regeneron/Sanofi’s PSCK9 Inhibitor Might Need Two-Week Dosing Schedule

Fully human antibody for hypercholesterolemia is set to enter Phase III next month, and while the firms aren’t discussing the protocol, recent data suggest that REGN727/SRA236553 may need dosing every two weeks, rather than the more convenient monthly schedule.

As competition heats up in the race to find innovative lipid-management drugs that work on patients when statins do not, first-to-market positioning, efficacy and pricing are likely to be top differentiators.

Furthest along in so far the high-profile PCSK9 inhibitor class are Regeneron Pharmaceuticals Inc. and Sanofi with a...

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