PledPharma Readies PledOx For Phase III FDA Talks And Partnering

PledPharma unveiled potentially transforming Phase IIb top-line results for its new medicine PledOx, which aims to reduce severe side effects from chemotherapy. The Swedish small cap firm now will engage with regulators to map out its Phase III program – and woo potential commercial partners for the needed financing.

PledPharma AB’s Phase IIb studies to reduce chemotherapy-induced side effects in colorectal cancer have given the Swedish biotech what it needs to initiate discussions with regulators to plan Phase III trials, and also credibility to approach would-be commercial partners.

Headline results from the Phase IIb study of PledOx (calmangafodipir) showed a clinically relevant reduction in the incidence of sensory...

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