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Pfizer Eyes Xeljanz Expansion To Ulcerative Colitis

 
• By Jessica Merrill

Two Phase III trials testing the oral JAK inhibitor in ulcerative colitis met their primary endpoints, but Pfizer is awaiting the results of another Phase III maintenance study before filing for a label extension.

Pfizer Inc. released positive Phase III data from two induction trials testing its oral Janus kinase inhibitor Xeljanz (tofacinitib) in patients with the inflammatory bowel disease ulcerative colitis, but the company will await the results of ongoing Phase III studies before filing for an indication expansion.

The company announced the top-line results from the first two trials Sept. 21.

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