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Denying Inappropriate PCSK9 Prescriptions Keeps Costs In Check For Express Scripts

 
• By Jessica Merrill

About 50% of the scripts being written for the cholesterol-lowering drugs are being denied, Chief Trade Relations Officer Everett Neville indicated during the Pharmaceutical Strategy Conference.

Express Scripts Holding Co.’s Chief Trade Relations Officer Everett Neville said the pharmacy benefit manager’s approach to managing the new PCSK9 inhibitors – Amgen Inc.’s Repatha and Sanofi/Regeneron Pharmaceuticals Inc.’s Praluent – is very different from its strategy in hepatitis C, where it ended up excluding one firm's product in favor of another.

“Yes, cost is an issue. They are overpriced, but the most important factor with the PCSK9s is that not many patients should be on the drug today, based on the...

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