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GSK’s Breo Fails To Reach Peak In SUMMIT Survival Study

 
• By Jessica Merrill

The UK pharma had pinned much of its long-term hopes for Breo on successful results of SUMMIT, which compared the morbidity and mortality of COPD patients at increased risk of cardiovascular disease taking Breo versus placebo.

The negative news keeps piling on for GlaxoSmithKline PLC’s respiratory franchise with Advair Diskus’ sales flagging because of increased competition and pricing pressure and the next-generation drug Breo Ellipta failing to make up the lost ground. Now, an important survival study on which GSK had pinned much of its long-term hopes for Breo failed to show a survival benefit versus placebo.

GSK had hoped the results of SUMMIT would improve the case for Breo (fluticasone/vilanterol), a once-daily inhaled corticosteroid/long-acting beta2-agonist (ICS/LABA)...

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