Paratek And The “Blockbuster” vs. Steady “Stewardship” Approach In Antibiotics

US FDA Antimicrobial Drugs Advisory Committee Chair Baden offers warning about “overuse” to emerging antibiotic sponsor.

Antibiotic resistant bacteria closeup biofilm

There was a seemingly paradoxical moment towards the end of Paratek Pharmaceuticals Inc.’s omadacycline US FDA advisory committee meeting that exemplifies how many stakeholders feel about new antibiotics: They encourage their development, but aren't exactly enthusiastic about their use.

The Antimicrobial Drugs Advisory Committee had voted overwhelmingly to support approval of two indications at the Aug. 8 meeting: acute bacterial skin and skin structure infections (ABSSSI) and community-acquired bacterial pneumonia (CABP). (

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