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Building A Bridge To A COVID-19 Vaccine: Hydroxychloroquine And BCG Lead Prevention Pipeline

 
• By Bridget Silverman

More than 40 Phase III trials are assessing pre- and post-exposure prophylaxis of SARS-CoV-2 infection.

Coronavirus globe

While the world waits for a COVID-19 vaccine and effective therapies, pre- and post-exposure prophylaxis strategies for people at risk of SARS-CoV-2 infection are being tested in more than 40 Phase III trials worldwide, including the first two trials to receive support from the COVID-19 Therapeutics Accelerator coalition.

Pre- and post-exposure prophylaxis (PrEP/PEP) trials registered on clinicaltrials.gov are overwhelmingly evaluating already-available generic medicines; more than half are evaluating the (sometimes politicized) anti-malarial hydroxychloroquine

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