Coronavirus Notebook: UK To Run Vaccine Challenge Studies, CEPI Expands Manufacturing Network

Two new projects have begun, one on standardizing the assessment of immune responses in individuals vaccinated in clinical trials, the other to improve understanding of potential immunity in patients who have been infected with SARS-CoV-2.

Vaccination against the new Corona Virus SARS-CoV-2: A syringe being drawn up with SARS-CoV-2 vaccination.
Challenge trials should be useful in developing coronavirus vaccines • Source: Shutterstock

One of the big stories of the week is the UK’s announcement that human challenge studies are to be conducted next year in an effort to accelerate the development of successful COVID-19 vaccine candidates.

Under the plans, a vaccine candidate that has been shown to be safe in initial clinical trials will be given to “a small number of carefully selected healthy adult volunteers” who will then

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