Gene Therapy HTA: How Do The European, Australian And Canadian Systems Shape Up?

A report comparing the health technology assessment methods used in nine European countries, Australia and Canada found that England has the most favorable reimbursement landscape for gene therapies – but outlined several areas for improvement across the board.

There are six main actions that health technology assessment organizations should implement to capture the value of gene therapies, according to researchers from the UK’s Office for Health Economics (OHE). Yet, the organization suggested in a recent report, wide variations in the HTA methods used within different countries demonstrate the importance of continued changes to HTA methodologies and evidence generation to enable the potential benefits of gene therapies to be realized.

Some of its recommended actions include the development of standards for the use of real-world evidence and surrogate endpoints in...