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WHO To Finalize Preferred & Critical Characteristics Of New Mpox Human Vaccines

 
• By Vibha Sharma

To help sponsors developing candidate mpox vaccines, the World Health Organization will soon be finalizing guidance on the preferred and minimum characteristics these products must satisfy regarding efficacy, dose regimen and other aspects to secure regulatory approval.

Monkeypox distribution. Graph of smallpox infections. Global Pandemic Monkeypox. 3d image
There is currently no globally approved mpox vaccine for widespread use • Source: Shutterstock

The World Health Organization will soon be examining the feedback drawn by its revised target product profile (TPP) for human vaccines for mpox, which specifies that the preferred efficacy of new vaccines should ideally be greater than 90%, with a minimum acceptable efficacy of over 60%.

Stakeholders had until 23 August to comment on the updated draft TPP, which is intended for vaccine scientists, product developers, manufacturers and funding agencies, and describes the

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