Panel Recommends Against OTC Singulair Due To Off-Label Use Risk

FDA’s Nonprescription Drug Advisory Committee votes against recommending approval after weighing the risks and benefits of switching Merck’s Singulair Allergy 10 mg montelukast sodium for allergy relief.

A panel of experts discouraged FDA from switching Merck & Co. Inc.’s Singulair Allergy from Rx to OTC because the risk of off-label use and neuropsychiatric adverse events do not outweigh the “modest” benefit of allergy relief.

At a May 2 meeting of FDA’s Nonprescription Drug Advisory Committee, 11 of the 15 members voted that 10 mg montelukast sodium could not be used safely in the OTC...

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