Genentech withdraws psoriasis drug Raptiva in US over PML risk

Genentech is to withdraw its psoriasis therapy Raptiva (efalizumab) in the US based on its association with an increased risk of developing progressive multifocal leucoencephalopathy (PML), a rare and potentially fatal brain infection.

Genentech is to withdraw its psoriasis therapy Raptiva (efalizumab) in the US based on its association with an increased risk of developing progressive multifocal leucoencephalopathy (PML), a rare and potentially fatal brain infection.

Three patients taking the monoclonal antibody therapy were diagnosed with cases of PML, two of which were fatal. A fourth...

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