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AIM-HIGH misses its mark, but hits Abbott and the "HDL hypothesis"

 
• By Nancy Faigen

Hopes of taking cardiovascular adverse event prevention to the next level by raising levels of the "good" HDL-cholesterol have been dealt another blow with the failure of the AIM-HIGH study of Abbott's extended-release niacin product Niaspan.

Hopes of taking cardiovascular adverse event prevention to the next level by raising levels of the "good" HDL-cholesterol have been dealt another blow with the failure of the AIM-HIGH study of Abbott's extended-release niacin product Niaspan.

The trial sponsor, the US National Heart Lung and Blood Institute, announced on 26 May that it had halted study...

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