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Positive subgroup analysis provides additional boost to Trius' skin infection antibiotic

All eyes are now on Trius Therapeutics' second ongoing pivotal Phase III trial investigating its antibiotic, tedizolid phosphate, after the company reported positive, if disparate, results from a subgroup analysis of its first Phase III study (TR701-112) of the product in patients with acute bacterial skin and skin structure infections (ABSSSI).

All eyes are now on Trius Therapeutics' second ongoing pivotal Phase III trial investigating its antibiotic, tedizolid phosphate, after the company reported positive, if disparate, results from a subgroup analysis of its first Phase III study (TR701-112) of the product in patients with acute bacterial skin and skin structure infections (ABSSSI).

The new data confirm the drug's efficacy in a subgroup of patients with cellulitis but suggest higher efficacy in European subjects than in US patients.

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