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Sickle cell therapies: GlycoMimetics and others target underlying causes

 
• By Mandy Jackson

The standard of care in sickle cell anemia is treatment of pain during vaso-occlusive crisis (VOC) that occurs when sickled cells adhere and block the flow of blood and oxygen, but there are a handful of therapies in development that seek to transform treatment of the disease by interrupting blockages or preventing sickled cells.

The standard of care in sickle cell anemia is treatment of pain during vaso-occlusive crisis (VOC) that occurs when sickled cells adhere and block the flow of blood and oxygen, but there are a handful of therapies in development that seek to transform treatment of the disease by interrupting blockages or preventing sickled cells.

GlycoMimetics says its drug rivipansel (GM 1070) could be the first therapy to disrupt the underlying cause of sickle cell...

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