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The end is nigh for GSK's darapladib

 
• By Alexandra Shimmings

GlaxoSmithKline's investigational Lp-PLA 2 inhibitor darapladib has failed in a second Phase III study, SOLID-TIMI 52, all but extinguishing any hopes for the product.

GlaxoSmithKline's investigational Lp-PLA 2 inhibitor darapladib has failed in a second Phase III study, SOLID-TIMI 52, all but extinguishing any hopes for the product.

Top-line results show that the 13,000-patient trial missed its primary endpoint of a reduction of major coronary events, versus placebo when added to standard of care in adults

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