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Novartis winces as GSK's ofatumumab crashes in DLBCL

 
• By Sukaina Virji

GlaxoSmithKline and Genmab's Phase III study (ORCHARRD) of ofatumumab (Arzerra) in diffuse large B-cell lymphoma (DLBCL) has failed to meet its primary endpoint of progression free survival (PFS).

GlaxoSmithKline and Genmab's Phase III study (ORCHARRD) of ofatumumab (Arzerra) in diffuse large B-cell lymphoma (DLBCL) has failed to meet its primary endpoint of progression free survival (PFS).

There was no significant difference between the two treatment arms: ofatumumab plus chemotherapy versus rituximab (MabThera/Rituxan) plus chemotherapy. Based on...

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Glenmark Chief On IGI’s Landmark Trispecific Deal: Strong Data Excited AbbVie

 
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Four Chinese Firms Snag Global First-In-Class Approvals In China

 
• By Dexter Jie Yan

Four Chinese companies have won approvals in China, the first anywhere, for novel drugs for diffuse large B-cell lymphoma, certain types of non-small cell lung cancer and influenza A.

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IGI CEO Cyril Konto said in an interview that his company picked AbbVie for its agility, drug development acumen and expertise in areas like intellectual property and legal affairs.

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• By Kevin Grogan

The osteogenesis imperfecta drug stumbled in a second interim analysis.

Investors Back Nuclidium’s Next-Gen Copper-Based Radiopharmaceuticals

 
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Taiho’s Oral, Mutation-Agnostic DMD Candidate Misses Phase III Endpoint

 
• By Lisa Takagi

The oral, twice-daily candidate was expected to control decline in motor function in DMD patients regardless of their gene mutations.