BioNotebook: Five VC deals, three public financings, and a round of layoffs

Syros raises $53m Series B; Aileron gets $33m more for Series E; Imago closes $26.5m Series A; $20m equity investment for Xcovery; Affinivax launches with $4m; Synergy sells convertible notes; Regulus, Vanda price stock offerings; and Impax cuts 49 jobs.