BioMarin Pharmaceutical is to buy rare disease-focused Prosensa for $680m in cash and $160m in contingent milestones if Prosensa's Duchenne muscular dystrophy product – the GSK-reject drisapersen – is approved quickly in the US and Europe.
Drisapersen had been partnered with GlaxoSmithKline but the big pharma pulled out of the deal following drisapersen's failure in the Phase III DEMAND study last year, which showed that the antisense oligonucleotide did not meet the primary endpoint of statistically significant improvement in the six-minute walking distance (6MWD) test compared with placebo (
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