Merck & Co.'s bezlotoxumab for the treatment of recurrent clostridium difficile (C diff) infections is "a big step" for treatment of the debilitating and potentially deadly gut infection, according to Dale Gerding, a professor at Loyola University Chicago Stritch School of Medicine and a lead investigator for the monoclonal antibody's Phase III clinical trials.
Bezlotoxumab and Merck's actoxumab are the only antibody therapies in clinical development for C diff infections, which are characterized by...
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