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Incyte and Merck Push I/O Drug Forward

 
• By Lisa LaMotta

Incyte and Merck & Co. have decided to move a combination of their respective immunotherapies into a pivotal Phase III trial as a first-line therapy for patients with advanced metastatic melanoma. The trial, set to begin in the first half of 2016, will combine Incyte's IDO1 inhibitor epacadostat with Merck's already-approved programmed death-1 (PD-1) antagonist Keytruda (pembrolizumab).

Financial details of the collaboration were not disclosed.

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