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Incyte and Merck Push I/O Drug Forward

 
• By Lisa LaMotta

Incyte and Merck & Co. have decided to move a combination of their respective immunotherapies into a pivotal Phase III trial as a first-line therapy for patients with advanced metastatic melanoma. The trial, set to begin in the first half of 2016, will combine Incyte's IDO1 inhibitor epacadostat with Merck's already-approved programmed death-1 (PD-1) antagonist Keytruda (pembrolizumab).

Financial details of the collaboration were not disclosed.

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ASCO: Carvykti Data Raise Possibility Of Myeloma Cure

 
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Merus Raises $300m After ASCO Success

 
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Bayer Boosted By Third FDA Approval For Nubeqa

 
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Vigil’s Iluzanebart Disappoints In Rare Neurodegenerative Disease

 
• By Jessica Merrill

The Phase II TREM2 agonist is not part of Sanofi’s planned acquisition.

Merus Raises $300m After ASCO Success

 
• By Andrew McConaghie

The company is raising the money to fuel development of its head and neck cancer candidate, petosemtamab, on the back of promising early data. Some analysts are stopping short of declaring it the winner against a rival product from Bicara, however.