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FDA: AZ/Ardea Gout Drug Modest Efficacy, Safety Concerns

 
• By Donna Young

An experimental gout drug from AstraZeneca plc unit Ardea Biosciences Inc., known as lesinurad, demonstrated only modest efficacy in clinical trials and has some concerning adverse cardiovascular (CV) and renal-related effects, FDA drug reviewers said on Oct. 21.

An experimental gout drug from AstraZeneca plc unit Ardea Biosciences Inc., known as lesinurad, demonstrated only modest efficacy in clinical trials and has some concerning adverse cardiovascular (CV) and renal-related effects, FDA drug reviewers said on Oct. 21.

Regulators' analysis of lesinurad, which Ardea is seeking to market under the brand-name Zurampic, came ahead of an Oct. 23...

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