MacroGenics, Merck Seize Gastric Cancer Opportunity With Margetuximab, Keytruda Combo

MacroGenics Inc. will study the ability of margetuximab to enhance the immune system's destruction of HER2-positive tumors in a Phase Ib/II clinical trial to evaluate the monoclonal antibody in combination with Merck & Co.'s PD-1 inhibitor Keytruda (pembrolizumab) in advanced gastric cancer.

Rockville, Maryland-based MacroGenics expects to begin patient enrollment for the trial, which will test the drug combination's safety in Phase...

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