Johnson & Johnson's long-awaited chemotherapy Yondelis (trabedectin) is finally approved for sarcoma in the US, having been approved in multiple other markets already, but leading a wave of potential new entrants in an area of high unmet need.
J&J's Yondelis Leads New Wave Of Sarcoma Drugs
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The German firm’s chairman, Hubertus von Baumbach, is adopting a ‘wait-and-see’ approach to the threat of pharma tariffs.
With new Phase II data, Edgewise asserted that EDG-7500, a sarcomere modulator, could offer better efficacy and safety than cardiac myosin inhibitors in hypertrophic cardiomyopathy.
Strong sales growth for the German group’s SGLT2 inhibitor in 2024
The firm has lofty ambitions for the aldosterone synthase inhibitor to treat hypertension and kidney disease.
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Following the near-total dominance of IgG antibodies, the UK group is backing the potential of IgA and IgE-based therapies to transform cancer treatment with the purchase of US-headquartered TigaTx.
By allowing it to enter the brain more easily, trontinemab’s brain shuttle brings more patients to ‘amyloid zero’ levels faster, and with fewer brain swelling side effects.
BeiGene’s Phase III ociperlimab joins the list of failed TIGIT inhibitors, as candidates from Roche, Merck & Co. and others have failed late-stage studies.