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Gene Editing Deal Broadens Vertex's CF Base, Doubles CRISPR's Cash

 
• By Mandy Jackson

Vertex Pharmaceuticals made a big financial commitment to expand its cystic fibrosis portfolio beyond drugs for patients with specific genetic mutations to gene-editing therapies that may cure CF via a new partnership with CRISPR Therapeutics that more than doubles the startup firm's cash balance.

Vertex Pharmaceuticals made a big financial commitment to expand its cystic fibrosis portfolio beyond drugs for patients with specific genetic mutations to gene-editing therapies that may cure CF via a new partnership with CRISPR Therapeutics that more than doubles the startup firm's cash balance.

Boston-based Vertex will pay $105m up front, including a $30m equity investment in CRISPR, to develop therapies based on clustered,...

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More from Musculoskeletal

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Lilly’s Muscle Builder Looks Strong In GLP-1 Obesity Combo

 
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Sarepta Market Dynamics For Elevidys Imperiled By Second Patient Death

 
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Lilly Looks For Muscle-Sparing Candidates In Pact With Juvena

 
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Deal Snapshot: Including its internal efforts with bimagrumab, Lilly has been seeking a muscle-sparing therapy to complement GLP-1 obesity drugs, such as Zepbound.

More from Therapy Areas

In Brief: Opus Gears Up For FDA Filing In Presbyopia

 
• By Sushmita Panda

Data from a second pivotal trial support a filing in the US for Opus Genetics’ phentolamine ophthalmic solution, to treat presbyopia.

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In Brief: Sanofi Cements Support For Adagene

 
• By Kevin Grogan

Deal Snapshot: The French drugmaker has been shifting its investments away from cancer to focus on immunology and inflammation but it continues to seek out interesting early-stage oncology assets.