Cardioxyl Buy To Resuscitate Bristol's CV Pipeline?

While Bristol-Myers Squibb has been at the forefront of immuno-oncology, the big pharma has lagged behind competitors in some other therapeutic areas. The New York pharma is aiming to correct that by picking up a small cardiology focused biotech to get its hands on a mid-stage program that is high risk, but could also hold high reward.

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Major Cash Injection Advances Augustine’s HDAC6 Hopes

 
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The Belgian firm banks nearly €77.7m to push its Charcot-Marie-Tooth to proof-of-concept.

Alnylam Joins Competitive ATTR-CM Market With Amvuttra Approval

 

Amvuttra will target a substantially larger patient population with a new indication, but it is third to market behind Pfizer’s Vyndaqel and Bridge Bio’s Attruby and will cost more.

What’s Hot And What’s Not For Sofinnova

 
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Chairman Antoine Papiernik spoke to Scrip about the therapeutic areas that where the VC major is looking at to invest its considerable cash pile.

Mineralys Seeks First-To-Market Edge In Uncontrolled Hypertension

 
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Battling AstraZeneca in the aldosterone inhibitor space, Mineralys reports Phase III data showing lorundrostat can significantly decrease uncontrolled/resistant blood pressure at six weeks.

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Soleno’s Vykat Gains First Prader-Willi Syndrome Approval, Rivals To Follow

 

After a long wait for patients, Vykat has become the first drug approved for Prader-Willi syndrome symptoms, opening the market up for Soleno and future challengers.

Wave Aspires To Accelerated Approval In DMD With 48-Week Data

 
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With its exon 53-skipping candidate already showing promise in 24-week data, Wave now has 48-week data showing improvements in muscle health and functional outcomes.

Rybrevant/Lazcluze Survival Win Could Overcome Tagrisso’s Convenience Advantage

 

J&J is confident that its bispecific antibody/kinase inhibitor combo’s overall survival win over AstraZeneca’s single-agent pill will shift the standard of care.