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YM BioSciences plans pivotal NSCLC trial for nimotuzumab

 
• By Malini Guha

YM BioSciences' experimental EGFR-targeted humanised monoclonal antibody drug nimotuzumab (YMB1000-015) will not progress to a pivotal trial in colorectal cancer at this time, but the Canadian company instead proposes to advance it into two other pivotal trials this year, including one in non-small cell lung cancer (NSCLC), which it believes could result in faster marketing approval.

YM BioSciences' experimental EGFR-targeted humanised monoclonal antibody drug nimotuzumab (YMB1000-015) will not progress to a pivotal trial in colorectal cancer at this time, but the Canadian company instead proposes to advance it into two other pivotal trials this year, including one in non-small cell lung cancer (NSCLC), which it believes could result in faster marketing approval.

YM's chief executive, David Allan, said the company was "most encouraged" by the results of a single-arm Phase II study testing nimotuzumab in patients with metastatic colorectal cancer plus the...

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