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Another Simtuzumab Failure For Gilead

 
• By Lisa LaMotta

Gilead Sciences Inc. has chalked up its second failure for its lysyl oxidase-like-2 (LOXL2) inhibitor simtuzumab, virtually killing its prospects, despite continuing trials in other indications.

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Compounding Unlikely To Solve GLP-1 Affordable Access Issues

 
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The end of semaglutide and tirzepatide shortages means large-scale compounding is declining, ICER noted. But compounded versions – and the demand for them – are likely here to stay.

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Multiple Tactics Likely Needed To Control Obesity Drug Costs

 
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Rhythm Anticipates Smooth Sailing For Setmelanotide After Phase III Success

 
• By Alaric DeArment

The company plans a tiered sales approach as it targets endocrinologists for hypothalamic obesity, which is more widely diagnosed than its current indication for Bardet-Biedl syndrome.

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Ferring’s Faith In Bladder Cancer Gene Therapy Starts To Pay Off

 
• By Kevin Grogan

Adstiladrin sales hit €70m in first full year on the market

Multiple Tactics Likely Needed To Control Obesity Drug Costs

 
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ICER’s new white paper pointed to estimates that the GLP-1 drugs may result in more than $100bn in annual spending, highlighting the need to rein in costs.

Cartesian Maps Out CAR-T Strategy With Simpler Logistics In Mind

 
• By Alaric DeArment

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