Performance-based reimbursement agreements with US payers, like the deals that Novartis AG recently struck with Cigna Corp. and Aetna Inc. for the heart failure drug Entresto (sacubitril/valsartan), are rare, but Novartis US Head Christi Shaw said she's hopeful that the concept will catch on.
If Entresto reduces the number of heart failure patients who require hospital stays, then Cigna and Aetna will pay a higher price for the drug, but they'll get a discount if the 21% reduction in hospitalizations that Entresto produced in clinical trials is not repeated in the real world
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