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Finance Roundup: Tizona, Aspyrian Raise VC Cash; Two Biotechs Ready IPOs

 
• By Mandy Jackson

Immuno-oncology and targeted cancer therapies, especially when backed by seasoned drug development teams, continue to attract keen venture capital interest, as Tizona Therapeutics Inc. and Aspyrian Therapeutics Inc. demonstrated recently.

Immuno-oncology and targeted cancer therapies, especially when backed by seasoned drug development teams, continue to attract keen venture capital interest, as Tizona Therapeutics Inc. and Aspyrian Therapeutics Inc. demonstrated recently.

South San Francisco-based Tizona closed a $43m Series B round co-led by Canaan Partners and Abingworth to take its immuno-oncology candidates into the clinic, while Aspyrian in San Diego garnered...

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ASCO: Lupin Presents Early Data On PRMT5 Inhibitor

 
• By Vibha Ravi

ASCO sees the debut of Lupin’s PRMT5 inhibitor candidate LRNP7457, currently in Phase I studies in India. While no drug with this mechanism of action has been approved anywhere so far, several candidates are in clinical trials.

Bristol Will Pay BioNTech $1.5bn Up Front To Enter PD-L1xVEGF Space

 
• By Joseph Haas

BMS is guaranteeing BioNTech at least $3.5bn to share development costs and potential profits on the Phase III bispecific, to compete with Summit, Merck and Pfizer.

ASCO: IO Continues Climb To Earlier Use With AstraZeneca’s MATTERHORN, BMS’s NIVOPOSTOP

 
• By Mary Jo Laffler

Data presented at ASCO supports use of AZ’s Imfinzi for perioperative gastric cancer and BMS’s Opdivo for adjuvant treatment of head and neck cancer.

ASCO: DESTINY-Breast09 Strong, But May Need Mature OS Data To Change Practice

 
• By Alaric DeArment

Data from AstraZeneca/Daiichi’s breast cancer trial showed positive PFS, but some oncologists are waiting for confirmation of statistically significant OS benefit.

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ASCO: DESTINY-Breast09 Strong, But May Need Mature OS Data To Change Practice

 
• By Alaric DeArment

Data from AstraZeneca/Daiichi’s breast cancer trial showed positive PFS, but some oncologists are waiting for confirmation of statistically significant OS benefit.

Sanofi Plays It Safer With Blueprint Buy After Bumpy 2025

 
• By Kevin Grogan

But the French major is still keen on early-stage M&A.

BREAKING NEWS: Sanofi Bets $9.5bn To Bag Blueprint

 
• By Kevin Grogan

Buy boosts the French major's immunology pipeline.