Doctors who treat Crohn's disease are prescribing biologics more frequently than in the past to quickly reduce inflammation, but they're searching for alternatives to tumor necrosis factor (TNF) inhibitors to cut the side effect risks, and that is where the Johnson & Johnson subsidiary Janssen Biotech Inc. may find its best niche for Stelara (ustekinumab).
The Interleukin-12 (IL-12) and IL-23 antagonist is approved in 87 countries to treat psoriasis and in 71 countries to treat psoriatic arthritis, including the US and EU where Janssen is seeking approvals to treat Crohn's disease
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