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ASCO Round-Up: Array, Kite, Exelixis, Pfizer/Merck KGAA, Mylan, Novartis

 
• By Lisa LaMotta, Mary Jo Laffler, and Emily Hayes

The annual American Society of Clinical Oncology (ASCO) conference has been ongoing the last several days in Chicago, giving companies the chance to showcase their work in a range of cancers. Here's a look at some of the highlights.

Array BioPharma Inc. updated investors on the progress of combination trials for its BRAF inhibitor encorafenib, presenting results from a Phase II trial comparing a combination of encorafenib and cetuximab, with or without alpelisib, in patients with BRAF-positive colorectal cancer. The 102-patient study compared the double and triple regimens with historical benchmarks of survival.

According to the data, the double and triple regimens showed a median overall survival (OS) of 12.4 and 13.1 months,...

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ASCO: Kite’s Glioblastoma CAR-T Highlights Solid Tumor Progress

 
• By Alaric DeArment

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ASCO: Carvykti Data Raise Possibility Of Myeloma Cure

 
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Merus Raises $300m After ASCO Success

 
• By Andrew McConaghie

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• By Sushmita Panda

In a turn of fortunes, Lyra Therapeutics has reported positive Phase III results for LYR-210 in chronic rhinosinusitis, boosting hopes for US approval. The company plans to submit an NDA and pursue further trials, but its cash position is precarious.

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New Regenxbio DMD Data Support Gene Therapy Accelerated Approval

 
• By Joseph Haas

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