In the Midst Of A Shakeout, Biotech VCs Must Embrace New Partners, New Math

With funds and firms closing, a new reality awaits those who survive until the next economic upswing. Some of the elements are already in place, such as VCs' willingness to take capped returns and exits via risk-sharing contingency-based acquisitions. The emphasis on capital efficiency may change the types of companies VCs can afford to back, and corporate funds are now a vital part of biotech venture, especially in the early stages.

by Alex Lash

Whether the economy recovers or derails into recession again, it's becoming clear that the drug world, and especially the financing of crucial early-stage innovation – the industry's fuel for decades – will not emerge from the crisis in the same form. The pressures are already forging new models and altered expectations among biotech's venture investors – those that survive. The allure of venture as an alternate asset class has dimmed, and venture investors are increasingly hard pressed to find backers. This financial dearth has kick-started a shakeout with predictions that anywhere from a quarter to 40% of venture firms will not be able to raise new funds

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