These days, most start-up companies intent on developing a novel treatment for nearly any disease make a point of talking about their drug candidate’s presumed mechanism of action. It is pretty much de rigueur that a would-be drugmaker will discuss molecular something: if not the candidate itself, then certainly its target. But Cellceutix Corp. is not a typical start-up. Founded in June 2007, it became a publicly traded company through a reverse merger in December of that year. While the company appreciates the buzz that its anti-cancer candidate is generating, it is being a bit more tight-lipped about Prurisol, its novel drug candidate for psoriasis.
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CEO Paul Stoffels said gaining US clearance for an IND for its novel CAR-T product was demanding, but now opens up a pathway towards a pivotal study starting in 2025.
A final rejection of Leqembi could also spell the same fate for Lilly’s rival drug but public outcry and demand for Alzheimer’s therapies might force the regulator’s hand
CEO Bill Anderson tells Scrip that the German group looks at potential in-licensing opportunities across every stage of the pipeline “but as you know, good value is a lot harder to come by in the late stage.”
Byterna, Starna, Vivacta and DeliNova ride surging investor sentiment on in vivo CAR-T assets to secure venture funding.
Sagimet may shift focus to later-stage MASH while it lines up Phase III financing. Altimmune expects its dual agonist to show efficacy and tolerability, while GSK is readying efimosfermin as the third FGF21 analog into Phase III for MASH.
