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Oncolytics' Cleverly Cut Subgroup Data Unlikely To Save Reolysin In NSCLC

 
• By Lucie Ellis-Taitt

August appears to be month of bad news for clinical developments in non-small cell lung cancer (NSCLC). Following Bristol-Myers Squibb Co.'s shocking Phase III failure for Opdivo (nivolumab) in first-line NSCLC, Oncolytics Biotech Inc. has also reported disappointing data for its lung cancer drug Reolysin.

Men and women split on sides, separation crack. Concept 3D illustration.

Oncolytics Biotech reported less than impressive Phase II NSCLC data for its cancer drug Reolysin (pelareorep) this week – and despite the company's best attempt to find statistical significant data in subgroup analyses, analysts are not convinced.

The Canadian firm reported on Aug. 10 data split by gender from the Phase II IND211 study, which enrolled patients with both non-squamous (adenocarcinoma) and squamous cell histology. Patients with...

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