Genentech, BioNTech Pact Aims To Make Targeted Cancer Vaccines

Genentech will tap expertise of privately-held BioNTech in a collaboration aimed at developing individually tailored vaccines for use against a broad range of cancers, which the duo says offers “a new treatment paradigm” for oncology.

Syringes stuck in a dartboard

Genentech Inc. and Germany’s BioNTech AG believe that together they can leverage the US-based Roche division’s portfolio of approved and investigational cancer immunotherapies and the privately-held biotech’s proprietary mRNA cancer vaccine technology platform to develop bespoke cancer vaccines for individual patients.

Most approaches to cancer vaccines have been unsuccessful due to difficulties identifying the correct cancer targets, or antigens, to vaccinate against. But the duo says that with advanced sequencing and...

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